Well-being is a fact, not just a feeling
Harris's foundational move is to treat well-being as a real, physical phenomenon rooted in brain states, not a purely subjective preference immune to investigation. If flourishing and suffering correspond to identifiable patterns in conscious experience — and by extension in the brains producing that experience — then claims about what increases or diminishes them are, in principle, factual claims, checkable against evidence rather than merely asserted.
This directly challenges the common assumption that "science tells us what is, morality tells us what ought to be," treating that split as a category error rather than a permanent boundary. If oughts are really claims about what promotes or damages conscious well-being, they collapse into a special case of is-claims.
Harris acknowledges this doesn't yet give us a precise science of ethics, but insists the possibility of one is enough to dismantle the idea that morality sits permanently beyond empirical reach. If well-being is real and measurable in principle, morality has facts to discover, not just opinions to trade.